FAAP20 Antibody

Size

100ug

Clone Number

Aliases

C1orf86 antibody; CA086_HUMAN antibody; Chromosome 1 open reading frame 86 antibody; FAAP20 antibody; Fanconi anemia associated protein of 20 kDa antibody; FP7162 antibody; RP11-181G12.3 antibody; Uncharacterized protein C1orf86 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q6NZ36

Immunogen

Recombinant Human Fanconi anemia core complex-associated protein 20 protein (14-179AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background

Component of the Fanconi anemia (FA) complex required to recruit the FA complex to DNA interstrand cross-links (ICLs) and promote ICLs repair. Following DNA damage recognizes and binds \'Lys-63\'-linked ubiquitin generated by RNF8 at ICLs and recruits other components of the FA complex. Promotes translesion synthesis via interaction with REV1.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

FAAP20

Research Areas

Cell biology