F12 Antibody

Size

100ug

Clone Number

Aliases

Factor XII antibody; Beta factor XIIa part 1 antibody; Beta factor XIIa part 2 antibody; Coagulation factor XII antibody; Coagulation factor XIIa heavy chain antibody; Coagulation factor XIIa light chain antibody; F12 antibody; F12 deficiency antibody; FA12_HUMAN antibody; Factor XII deficiency antibody; HAE3 antibody; HAEX antibody; HAF antibody; HAF deficiency antibody; Hageman factor antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

P00748

Immunogen

Recombinant Human Coagulation factor XII protein (486-600AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background

Factor XII is a serum glycoprotein that participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII first to alpha-factor XIIa and then trypsin cleaves it to beta-factor XIIa. Alpha-factor XIIa activates factor XI to factor XIa.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

F12

Research Areas

Cardiovascular