F11R Antibody, Biotin conjugated

Size

100ug

Clone Number

Aliases

CD 321 antibody; CD321 antibody; CD321 antigen antibody; ESTM33 antibody; F11 receptor antibody; F11R antibody; JAM 1 antibody; JAM A antibody; JAM antibody; JAM-1 antibody; JAM-A antibody; JAM1 antibody; JAM1_HUMAN antibody; JAMA antibody; JCAM antibody; Jcam1 antibody; Junction adhesion molecule 1 antibody; Junction adhesion molecule; mouse; homolog of antibody; Junctional adhesion molecule 1 antibody; Junctional adhesion molecule A antibody; KAT antibody; Ly106 antibody; PAM 1 antibody; PAM-1 antibody; PAM1 antibody; Platelet adhesion molecule 1 antibody; Platelet adhesion molecule antibody; Platelet F11 receptor antibody; PRO301 antibody; UNQ264 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9Y624

Immunogen

Recombinant Human Junctional adhesion molecule A protein (31-224AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA

Background

Seems to play a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3 (PubMed:11489913). The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly (By similarity). Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier (By similarity). Ligand for integrin alpha-L/beta-2 involved in memory T-cell and neutrophil transmigration (PubMed:11812992). Involved in platelet activation (PubMed:10753840).

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Biotin

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

F11R

Research Areas

Cardiovascular; Signal transduction