Ezrin(Phospho Tyr353) Polyclonal Antibody

Ab type

Primary antibody

Background

The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene.

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human Ezrin around the phosphorylation site of Tyr353. AA range:321-370

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

69413

synonyms

Ezrin; EZR; VIL2; Ezrin; Cytovillin; Villin-2; p81