EXT2 Antibody

Size

100ug

Clone Number

Aliases

Exostoses (multiple) 2 antibody; Exostosin 2 antibody; Exostosin-2 antibody; EXT2 antibody; EXT2_HUMAN antibody; Glucuronosyl N acetylglucosaminyl proteoglycan 4 alpha N acetylglucosaminyltransferase antibody; Glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase antibody; Multiple exostoses protein 2 antibody; N acetylglucosaminyl proteoglycan 4 beta glucuronosyltransferase antibody; Putative tumor suppressor protein EXT2 antibody; SOTV antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q93063

Immunogen

Recombinant Human Exostosin-2 protein (180-267AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background

Glycosyltransferase required for the biosynthesis of heparan-sulfate. The EXT1/EXT2 complex possesses substantially higher glycosyltransferase activity than EXT1 or EXT2 alone. Appears to be a tumor suppressor. Required for the exosomal release of SDCBP, CD63 and syndecan (PubMed:22660413).

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

EXT2

Research Areas

Signal transduction