EXT1 Antibody

Size

100ug

Clone Number

Aliases

4-alpha-N-acetylglucosaminyltransferase antibody; exostoses (multiple) 1 antibody; Exostosin 1 antibody; Exostosin glycosyltransferase 1 antibody; Exostosin-1 antibody; EXT antibody; EXT1 antibody; EXT1_HUMAN antibody; Glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase antibody; glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan antibody; Langer-Giedion syndrome chromosome region antibody; LGCR antibody; LGS antibody; Multiple exostoses protein 1 antibody; Multiple exostoses protein 1 homolog antibody; N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase antibody; Putative tumor suppressor protein EXT1 antibody; TRPS2 antibody; TTV antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q16394

Immunogen

Recombinant Human Exostosin-1 protein (28-171AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, WB; Recommended dilution: WB:1:1000-1:5000

Background

Glycosyltransferase required for the biosynthesis of heparan-sulfate. The EXT1/EXT2 complex possesses substantially higher glycosyltransferase activity than EXT1 or EXT2 alone. Appears to be a tumor suppressor. Required for the exosomal release of SDCBP, CD63 and syndecan (PubMed:22660413).

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

EXT1

Research Areas

Signal transduction