EXOC6 Rabbit Polyclonal Antibody

Ab type

Primary antibody

Background

The protein encoded by this gene is highly similar to the Saccharomyces cerevisiae SEC15 gene product| which is essential for vesicular traffic from the Golgi apparatus to the cell surface in yeast. It is one of the components of a multiprotein complex required for exocytosis. The 5' portion of this gene and two neighboring cytochrome p450 genes are included in a deletion that results in an autosomal-dominant form of nonsyndromic optic nerve aplasia (ONA). Alternative splicing and the use of alternative promoters results in multiple transcript variants. A paralogous gene encoding a similar protein is present on chromosome 2.

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from human EXOC6

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

88440

synonyms

EXOC6