EWSR1 Antibody

Size

100ul

Clone Number

Aliases

bK984G1.4 antibody; bK984G1.4 Ewing sarcoma breakpoint region 1 protein antibody; Ewing sarcoma breakpoint region 1 antibody; Ewing sarcoma breakpoint region 1 protein antibody; Ewings sarcoma EWS Fli1 type 1 oncogene antibody; EWS antibody; EWS oncogene antibody; EWS RNA binding protein 1 antibody; EWS_HUMAN antibody; EWSR 1 antibody; Ewsr1 antibody; EWSR1 protein antibody; RNA binding protein EWS antibody; RNA-binding protein EWS antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q01844

Immunogen

Recombinant Human RNA-binding protein EWS protein (1-300AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background

Might normally function as a transcriptionnal repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

EWSR1

Research Areas

Epigenetics and Nuclear Signaling; Cancer; Tags & Cell Markers