ABCbiolab
SKU:ABCB07850
EST4A Rabbit Polyclonal Antibody
EST4A Rabbit Polyclonal Antibody
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Ab type
Primary antibody
Background
This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics| such as cocaine and heroin| and endogenous substrates with ester| thioester| or amide bonds. They also participate in fatty acyl and cholesterol ester metabolism| and may play a role in the blood-brain barrier system. This gene| also called CES6| encodes a secreted enzyme| and may play a role in the detoxification of drugs and xenobiotics in neural and other tissues of the body and in the cerebrospinal fluid. Multiple transcript variants encoding different isoforms have been reported| but the full-length nature and/or biological validity of some variants have not been determined.
Reactivity
Human, Mouse
Clonality
Polyclonal
Host
Rabbit
Isotype
IgG
Immunogen
Synthesized peptide derived from human EST4A
Storage Stability
-20°C for 1 year
Concentration
1 mg/ml
MolecularWeight_Da
synonyms
EST4A; Carboxylesterase 4A; EC 3.1.1.-
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