EST3 Rabbit Polyclonal Antibody

Ab type

Primary antibody

Background

This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics| such as cocaine and heroin| and endogenous substrates with ester| thioester| or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism| and may play a role in the blood-brain barrier system. This gene is expressed in several tissues| particularly in colon| trachea and in brain| and the protein participates in colon and neural drug metabolism. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported| but the biological validity and/or full-length nature of some variants have not been determined.

Reactivity

Human, Rat, Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from human EST3

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

synonyms

EST3; Carboxylesterase 3; EC 3.1.1.1; Liver carboxylesterase 31 homolog