ESRRA Antibody

Size

100ul

Clone Number

Aliases

Err 1 antibody; ERR a antibody; ERR alpha antibody; ERR-alpha antibody; Err1 antibody; ERR1 protein antibody; ERR1_HUMAN antibody; ERRa antibody; ERRalpha antibody; ESRL 1 antibody; ESRL1 antibody; ESRR A antibody; Esrra antibody; Estrogen receptor like 1 antibody; Estrogen receptor related 1 antibody; estrogen receptor related receptor alpha antibody; Estrogen receptor-like 1 antibody; Estrogen related receptor alpha antibody; Estrogen-related receptor alpha antibody; Estrra antibody; hERR1 antibody; NR3B1 antibody; Nuclear receptor subfamily 3 group B member 1 antibody; Steroid hormone receptor ERR1 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

P11474

Immunogen

Recombinant Human Steroid hormone receptor ERR1 protein (1-423AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background

Binds to an ERR-alpha response element (ERRE) containing a single consensus half-site, 5\\\'-TNAAGGTCA-3\\\'. Can bind to the medium-chain acyl coenzyme A dehydrogenase (MCAD) response element NRRE-1 and may act as an important regulator of MCAD promoter. Binds to the C1 region of the lactoferrin gene promoter. Requires dimerization and the coactivator, PGC-1A, for full activity. The ERRalpha/PGC1alpha complex is a regulator of energy metabolism. Induces the expression of PERM1 in the skeletal muscle.

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

ESRRA

Research Areas

Epigenetics and Nuclear Signaling; Cancer; Metabolism; Signal transduction