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ELK Biotechnology

SKU:ES9892

UNC5C rabbit pAb

UNC5C rabbit pAb

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Size
Applications: WB;ELISA
Reactivity: Human;Mouse;Rat
Source: Rabbit
Dilution: WB 1:500-2000 ELISA 1:5000-20000
Immunogen: Synthesized peptide derived from human protein . at AA range: 60-140
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed_band(KD): 102kD
Human_gene_id: 8633
Human_swiss_prot_no: O95185
Subcellular_location: Cell membrane ; Single-pass type I membrane protein . Cell surface . Cell junction, synapse, synaptosome . Cell projection, axon . Cell projection, dendrite . Cell projection, growth cone . Cell projection, lamellipodium . Cell projection, filopodium .
Background: This gene product belongs to the UNC-5 family of netrin receptors. Netrins are secreted proteins that direct axon extension and cell migration during neural development. They are bifunctional proteins that act as attractants for some cell types and as repellents for others, and these opposite actions are thought to be mediated by two classes of receptors. The UNC-5 family of receptors mediate the repellent response to netrin; they are transmembrane proteins containing 2 immunoglobulin (Ig)-like domains and 2 type I thrombospondin motifs in the extracellular region. [provided by RefSeq, Jul 2008],
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