UNC5B rabbit pAb

Applications: WB;ELISA
Reactivity: Human;Rat;Mouse
Source: Rabbit
Dilution: WB 1:500-2000 ELISA 1:5000-20000
Immunogen: Synthesized peptide derived from human protein . at AA range: 350-430
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed_band(KD): 103kD
Human_gene_id: 219699
Human_swiss_prot_no: Q8IZJ1
Subcellular_location: Cell membrane ; Single-pass type I membrane protein . Membrane raft . Associated with lipid rafts. .
Background: This gene encodes a member of the netrin family of receptors. This particular protein mediates the repulsive effect of netrin-1 and is a vascular netrin receptor. This encoded protein is also in a group of proteins called dependence receptors (DpRs) which are involved in pro- and anti-apoptotic processes. Many DpRs are involved in embryogenesis and in cancer progression. Two alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Oct 2011],