MY18A rabbit pAb

Applications: WB;ELISA
Reactivity: Human;Mouse
Source: Rabbit
Dilution: WB 1:500-2000 ELISA 1:5000-20000
Immunogen: Synthesized peptide derived from human protein . at AA range: 1920-2000
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed_band(KD): 225kD
Human_gene_id: 399687
Human_swiss_prot_no: Q92614
Subcellular_location: Golgi apparatus . Golgi apparatus, trans-Golgi network . Golgi outpost . Cytoplasm, cytoskeleton, microtubule organizing center . Recruited to the Golgi apparatus by GOLPH3 (PubMed:19837035). Localizes to the postsynaptic Golgi apparatus region, also named Golgi outpost, which shapes dendrite morphology by functioning as sites of acentrosomal microtubule nucleation (By similarity). .; [Isoform 1]: Endoplasmic reticulum-Golgi intermediate compartment . Cytoplasm, cytoskeleton . Colocalizes with actin. .; [Isoform 2]: Cytoplasm . Lacks the PDZ domain (PubMed:12761286). Diffusely localized in the cytoplasm (PubMed:12761286). .; [Isoform 5]: Cell surface .
Background: caution:The TIAF1 protein is coded in the 3'-UTR region of MYO18A.,function:May be involved in the maintenance of the stromal cell architectures required for cell to cell contact.,similarity:Contains 1 IQ domain.,similarity:Contains 1 myosin head-like domain.,similarity:Contains 1 PDZ (DHR) domain.,subcellular location:Colocalizes with actin.,subcellular location:Lacks the PDZ domain. Diffusely localized in the cytoplasm.,subunit:Homodimer. Interacts with JAK3 and actin.,