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ELK Biotechnology

SKU:ES9541

CHD9 rabbit pAb

CHD9 rabbit pAb

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Size
Applications: IHC;IF
Reactivity: Human;Mouse
Source: Rabbit
Dilution: IHC-p 1:50-300
Immunogen: Synthesized peptide derived from part region of human protein
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed_band(KD): 318kD
Human_gene_id: 80205
Human_swiss_prot_no: Q3L8U1
Subcellular_location: Cytoplasm . Nucleus .
Background: function:Acts as a transcriptional coactivator for PPARA and possibly other nuclear receptors. Proposed to be a ATP-dependent chromatin remodeling protein. Has DNA-dependent ATPase activity and binds to A/T-rich DNA. Associates with A/T-rich regulatory regions in promoters of genes that participate in the differentiation of progenitors during osteogenesis.,PTM:Phosphorylated on serine and tyrosine residues.,sequence caution:Wrong choice of frame.,similarity:Belongs to the SNF2/RAD54 helicase family.,similarity:Contains 1 helicase ATP-binding domain.,similarity:Contains 1 helicase C-terminal domain.,similarity:Contains 2 chromo domains.,subunit:Interacts with PPARA. Probably interacts with ESR1 and NR1I3.,tissue specificity:Widely expressed at low levels. In bone marrow, expression is restricted to osteoprogenitor cells adjacent to mature osteoblasts.,
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