ACO2 rabbit pAb

Applications: WB;ELISA
Reactivity: Human;Mouse;Rat;Canine
Source: Rabbit
Dilution: Western Blot: 1/500 - 1/2000. ELISA: 1/5000.Not yet tested in other applications.
Immunogen: Synthesized peptide derived from human ACO2. at AA range: 421-470
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed_band(KD): 90kD
Human_gene_id: 50
Human_swiss_prot_no: Q99798
Subcellular_location: Mitochondrion .
Other_name: Aconitate hydratase, mitochondrial (Aconitase) (EC 4.2.1.3) (Citrate hydro-lyase)
Background: The protein encoded by this gene belongs to the aconitase/IPM isomerase family. It is an enzyme that catalyzes the interconversion of citrate to isocitrate via cis-aconitate in the second step of the TCA cycle. This protein is encoded in the nucleus and functions in the mitochondrion. It was found to be one of the mitochondrial matrix proteins that are preferentially degraded by the serine protease 15(PRSS15), also known as Lon protease, after oxidative modification. [provided by RefSeq, Jul 2008],