JAK2/3 (Phospho-Tyr966/939) Rabbit pAb

Applications: WB;ELISA;IHC
Reactivity: Human;Mouse;Rat
Source: Rabbit
Dilution: WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
Immunogen: Synthesized Phospho peptide derived from human JAK2/3.at AA range: T966
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Human_gene_id: 1132/1124
Human_swiss_prot_no: O60674/P52333
Subcellular_location: Endomembrane system ; Peripheral membrane protein . Cytoplasm . Nucleus .
Other_name: Tyrosine-protein kinase JAK2/JAK3 (EC 2.7.10.2) (Janus kinase 2/Janus kinase 3) (JAK-2/JAK-3)
Background: This gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis. [provided by RefSeq, Jul 2008],