NT-3 rabbit pAb

Applications: IHC;IF;ELISA
Reactivity: Human;Mouse;Rat
Source: Rabbit
Dilution: IHC-p 1:50-200, ELISA 1:10000-20000
Immunogen: Synthetic peptide from human protein at AA range: 180-230
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Human_gene_id: 4908
Human_swiss_prot_no: P20783
Subcellular_location: Secreted.
Other_name: Neurotrophin-3 (NT-3;HDNF;Nerve growth factor 2;NGF-2;Neurotrophic factor)
Background: The protein encoded by this gene is a member of the neurotrophin family, that controls survival and differentiation of mammalian neurons. This protein is closely related to both nerve growth factor and brain-derived neurotrophic factor. It may be involved in the maintenance of the adult nervous system, and may affect development of neurons in the embryo when it is expressed in human placenta. NTF3-deficient mice generated by gene targeting display severe movement defects of the limbs. The mature peptide of this protein is identical in all mammals examined including human, pig, rat and mouse. [provided by RefSeq, Jul 2008],