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ELK Biotechnology

SKU:ES8643

ASIC1 rabbit pAb

ASIC1 rabbit pAb

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Size
Applications: WB;IHC;IF;IHC-f;ELISA
Reactivity: Human;Mouse;Rat
Source: Rabbit
Dilution: WB 1:500-2000,IHC-p 1:500-200, ELISA 1:10000-20000
Immunogen: Synthetic peptide from human protein at AA range: 220-280
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed_band(KD): 55kD
Human_gene_id: 41
Human_swiss_prot_no: P78348
Subcellular_location: Cell membrane ; Multi-pass membrane protein . Localizes in synaptosomes at dendritic synapses of neurons. Colocalizes with DLG4 (By similarity). .
Other_name: Acid-sensing ion channel 1 (ASIC1;Amiloride-sensitive cation channel 2, neuronal;Brain sodium channel 2;BNaC2)
Background: This gene encodes a member of the acid-sensing ion channel (ASIC) family of proteins, which are part of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. Members of the ASIC family are sensitive to amiloride and function in neurotransmission. The encoded proteins function in learning, pain transduction, touch sensation, and development of memory and fear. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2012],
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