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ELK Biotechnology

SKU:ES8611

Cytokeratin 4 rabbit pAb

Cytokeratin 4 rabbit pAb

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Size
Applications: WB;ELISA
Reactivity: Human;Mouse;Rat
Source: Rabbit
Dilution: WB 1:500-2000, ELISA 1:10000-20000
Immunogen: Synthetic peptide from human protein at AA range: 200-260
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed_band(KD): 57kD
Human_swiss_prot_no: P19013
Subcellular_location: nucleus,intermediate filament,cell surface,keratin filament,intermediate filament cytoskeleton,
Other_name: Keratin, type II cytoskeletal 4 (Cytokeratin-4) (CK-4) (Keratin-4) (K4) (Type-II keratin Kb4)
Background: keratin 4(KRT4) Homo sapiens The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in differentiated layers of the mucosal and esophageal epithelia with family member KRT13. Mutations in these genes have been associated with White Sponge Nevus, characterized by oral, esophageal, and anal leukoplakia. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. [provided by RefSeq, Jul 2008],
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