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ELK Biotechnology

SKU:ES8505

VPS35 rabbit pAb

VPS35 rabbit pAb

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Size
Applications: WB;ELISA
Reactivity: Human;Mouse;Rat
Source: Rabbit
Dilution: WB 1:500-2000, ELISA 1:10000-20000
Immunogen: Synthesized peptide derived from VPS35 at AA range: 511-560
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed_band(KD): 92kD
Human_gene_id: 55737
Human_swiss_prot_no: Q96QK1
Subcellular_location: Cytoplasm. Membrane; Peripheral membrane protein. Endosome . Early endosome . Late endosome . Localizes to tubular profiles adjacent to endosomes. .
Other_name: Vacuolar protein sorting-associated protein 35 (hVPS35) (Maternal-embryonic 3) (Vesicle protein sorting 35)
Background: This gene belongs to a group of vacuolar protein sorting (VPS) genes. The encoded protein is a component of a large multimeric complex, termed the retromer complex, involved in retrograde transport of proteins from endosomes to the trans-Golgi network. The close structural similarity between the yeast and human proteins that make up this complex suggests a similarity in function. Expression studies in yeast and mammalian cells indicate that this protein interacts directly with VPS35, which serves as the core of the retromer complex. [provided by RefSeq, Jul 2008],
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