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ELK Biotechnology
SKU:ES8463
E-Selectin rabbit pAb
E-Selectin rabbit pAb
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Applications: WB;IHC;IF;ELISA
Reactivity: Human;Rat;Mouse;
Source: Rabbit
Dilution: IHC-p: 100-300.WB 1:500-2000, ELISA 1:10000-20000
Immunogen: The antiserum was produced against synthesized peptide derived from the N-terminal region of human SELE. AA range:100-150
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed_band(KD): 66kD
Human_gene_id: 6401
Human_swiss_prot_no: P16581
Subcellular_location: Cell membrane ; Single-pass type I membrane protein.
Other_name: selectin E
Background: The protein encoded by this gene is found in cytokine-stimulated endothelial cells and is thought to be responsible for the accumulation of blood leukocytes at sites of inflammation by mediating the adhesion of cells to the vascular lining. It exhibits structural features such as the presence of lectin- and EGF-like domains followed by short consensus repeat (SCR) domains that contain 6 conserved cysteine residues. These proteins are part of the selectin family of cell adhesion molecules. Adhesion molecules participate in the interaction between leukocytes and the endothelium and appear to be involved in the pathogenesis of atherosclerosis. [provided by RefSeq, Jul 2008],
Reactivity: Human;Rat;Mouse;
Source: Rabbit
Dilution: IHC-p: 100-300.WB 1:500-2000, ELISA 1:10000-20000
Immunogen: The antiserum was produced against synthesized peptide derived from the N-terminal region of human SELE. AA range:100-150
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed_band(KD): 66kD
Human_gene_id: 6401
Human_swiss_prot_no: P16581
Subcellular_location: Cell membrane ; Single-pass type I membrane protein.
Other_name: selectin E
Background: The protein encoded by this gene is found in cytokine-stimulated endothelial cells and is thought to be responsible for the accumulation of blood leukocytes at sites of inflammation by mediating the adhesion of cells to the vascular lining. It exhibits structural features such as the presence of lectin- and EGF-like domains followed by short consensus repeat (SCR) domains that contain 6 conserved cysteine residues. These proteins are part of the selectin family of cell adhesion molecules. Adhesion molecules participate in the interaction between leukocytes and the endothelium and appear to be involved in the pathogenesis of atherosclerosis. [provided by RefSeq, Jul 2008],
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