Vimentin (Phospho-Tyr38) rabbit pAb

Applications: WB;ELISA
Reactivity: Human;Mouse;Rat
Source: Rabbit
Dilution: WB: 1:500-10000 ELISA: 1:10000
Immunogen: Synthesized phospho-peptide around the phosphorylation site of human Vimentin (Phospho-Tyr38)
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed_band(KD): 51kD
Human_gene_id: 7431
Human_swiss_prot_no: P08670
Subcellular_location: Cytoplasm . Cytoplasm, cytoskeleton . Nucleus matrix . Cell membrane .
Other_name: VIM
Background: This gene encodes a member of the intermediate filament family. Intermediate filamentents, along with microtubules and actin microfilaments, make up the cytoskeleton. The protein encoded by this gene is responsible for maintaining cell shape, integrity of the cytoplasm, and stabilizing cytoskeletal interactions. It is also involved in the immune response, and controls the transport of low-density lipoprotein (LDL)-derived cholesterol from a lysosome to the site of esterification. It functions as an organizer of a number of critical proteins involved in attachment, migration, and cell signaling. Mutations in this gene causes a dominant, pulverulent cataract.[provided by RefSeq, Jun 2009],