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ELK Biotechnology

SKU:ES8383

EDA rabbit pAb

EDA rabbit pAb

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Applications: WB;IHC;IF;ELISA
Reactivity: Human;Mouse
Source: Rabbit
Dilution: Western Blot: 1/500 - 1/2000. IHC-p: 1:100-1:300. ELISA: 1/10000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human EDA. AA range:120-170
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed_band(KD): 42kD
Human_gene_id: 1896
Human_swiss_prot_no: Q92838
Subcellular_location: Cell membrane ; Single-pass type II membrane protein .; [Ectodysplasin-A, secreted form]: Secreted .
Other_name: EDA; ED1; EDA2; Ectodysplasin-A; Ectodermal dysplasia protein; EDA protein
Background: The protein encoded by this gene is a type II membrane protein that can be cleaved by furin to produce a secreted form. The encoded protein, which belongs to the tumor necrosis factor family, acts as a homotrimer and may be involved in cell-cell signaling during the development of ectodermal organs. Defects in this gene are a cause of ectodermal dysplasia, anhidrotic, which is also known as X-linked hypohidrotic ectodermal dysplasia. Several transcript variants encoding many different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
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