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ELK Biotechnology

SKU:ES7726

ULK1 rabbit pAb

ULK1 rabbit pAb

Regular price $250.00 USD
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Applications: IHC;IF;WB;ELISA
Reactivity: Human;Mouse
Source: Rabbit
Dilution: WB 1:500-2000,Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Immunogen: Synthesized peptide derived from the C-terminal region of human ULK1.
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Human_gene_id: 8408
Human_swiss_prot_no: O75385
Subcellular_location: Cytoplasm, cytosol . Preautophagosomal structure . Under starvation conditions, is localized to puncate structures primarily representing the isolation membrane that sequesters a portion of the cytoplasm resulting in the formation of an autophagosome. .
Other_name: ULK1; KIAA0722; Serine/threonine-protein kinase ULK1; Autophagy-related protein 1 homolog; ATG1; hATG1; Unc-51-like kinase 1
Background: catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Involved in axon growth. Plays an essential role in neurite extension of cerebellar granule cells.,similarity:Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. APG1/unc-51/ULK1 subfamily.,similarity:Contains 1 protein kinase domain.,subunit:Interacts with GABARAP and GABARAPL2.,tissue specificity:Ubiquitously expressed. Detected in the following adult tissues: skeletal muscle, heart, pancreas, brain, placenta, liver, kidney, and lung.,
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