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ELK Biotechnology

SKU:ES7566

CARD 14 rabbit pAb

CARD 14 rabbit pAb

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Size
Applications: IHC;IF;ELISA
Reactivity: Human;Mouse
Source: Rabbit
Dilution: Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human CAR14. AA range:291-340
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed_band(KD): 110kD
Human_gene_id: 79092
Human_swiss_prot_no: Q9BXL6
Subcellular_location: [Isoform 1]: Cytoplasm .; [Isoform 2]: Cytoplasm .; [Isoform 3]: Cytoplasm .
Other_name: CARD14; CARMA2; Caspase recruitment domain-containing protein 14; CARD-containing MAGUK protein 2; Carma 2
Background: This gene encodes a caspase recruitment domain-containing protein that is a member of the membrane-associated guanylate kinase (MAGUK) family of proteins. Members of this protein family are scaffold proteins that are involved in a diverse array of cellular processes including cellular adhesion, signal transduction and cell polarity control. This protein has been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Apr 2012],
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