CD318 (phospho Tyr707) rabbit pAb

Applications: WB;ELISA
Reactivity: Human;Mouse
Source: Rabbit
Dilution: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Immunogen: Synthesized phospho-peptide around the phosphorylation site of human CD318 (phospho Tyr707)
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed_band(KD): 140,80kD
Human_gene_id: 64866
Human_swiss_prot_no: Q9H5V8
Subcellular_location: [Isoform 1]: Cell membrane ; Single-pass membrane protein . Shedding may also lead to a soluble peptide.; [Isoform 3]: Secreted.
Other_name: CDCP1; TRASK; CUB domain-containing protein 1; Membrane glycoprotein gp140; Subtractive immunization M plus HEp3-associated 135 kDa protein; SIMA135; Transmembrane and associated with src kinases; CD antigen CD318
Background: This gene encodes a transmembrane protein which contains three extracellular CUB domains and acts as a substrate for Src family kinases. The protein plays a role in the tyrosine phosphorylation-dependent regulation of cellular events that are involved in tumor invasion and metastasis. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, May 2013],