Ribosomal Protein L5 rabbit pAb

Applications: WB;IP;IHC;IF;ELISA
Reactivity: Human;Mouse;Rat
Source: Rabbit
Dilution: WB 1:500-2000;IP 1:50-200;IHC-p 1:100-500;IF/ICC 1:100-500;ELISA 1:5000-20000
Immunogen: The antiserum was produced against synthesized peptide derived from human RPL5. AA range:161-210
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed_band(KD): 34kD
Human_gene_id: 6125
Human_swiss_prot_no: P46777
Subcellular_location: Cytoplasm . Nucleus, nucleolus .
Other_name: RPL5; MSTP030; 60S ribosomal protein L5
Background: Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L18P family of ribosomal proteins. It is located in the cytoplasm. The protein binds 5S rRNA to form a stable complex called the 5S ribonucleoprotein particle (RNP), which is necessary for the transport of nonribosome-associated cytoplasmic 5S rRNA to the nucleolus for assembly into ribosomes. The protein interacts specifically with the beta subunit of casein kinase II. Variable expression of this gene in colorectal cancers compared to adjacent normal tissues has been observed, although no correlation between the level of expression and the severity of the disease has been found