RBQ-3 rabbit pAb

Applications: WB;IHC
Reactivity: Human;Mouse;Rat
Source: Rabbit
Dilution: WB 1:500-2000;IHC-p 1:50-300
Immunogen: Synthesized peptide derived from RBQ-3 . at AA range: 190-270
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed_band(KD): 59kD
Human_gene_id: 5929
Human_swiss_prot_no: Q15291
Subcellular_location: Nucleus .
Other_name: RBBP5; RBQ3; Retinoblastoma-binding protein 5; RBBP-5; Retinoblastoma-binding protein RBQ-3
Background: This gene encodes a ubiquitously expressed nuclear protein which belongs to a highly conserved subfamily of WD-repeat proteins. The encoded protein binds directly to retinoblastoma protein, which regulates cell proliferation. It interacts preferentially with the underphosphorylated retinoblastoma protein via the E1A-binding pocket B. Three alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq, Jul 2010],