OAT rabbit pAb

Applications: WB;ELISA
Reactivity: Human;Mouse;Rat
Source: Rabbit
Dilution: Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.
Immunogen: Synthesized peptide derived from OAT . at AA range: 100-180
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed_band(KD): 48kD
Human_gene_id: 4942
Human_swiss_prot_no: P04181
Subcellular_location: Mitochondrion matrix .
Other_name: OAT; Ornithine aminotransferase; mitochondrial; Ornithine delta-aminotransferase; Ornithine--oxo-acid aminotransferase
Background: ornithine aminotransferase(OAT) Homo sapiens This gene encodes the mitochondrial enzyme ornithine aminotransferase, which is a key enzyme in the pathway that converts arginine and ornithine into the major excitatory and inhibitory neurotransmitters glutamate and GABA. Mutations that result in a deficiency of this enzyme cause the autosomal recessive eye disease Gyrate Atrophy. Alternatively spliced transcript variants encoding different isoforms have been described. Related pseudogenes have been defined on the X chromosome. [provided by RefSeq, Jan 2010],