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ELK Biotechnology
SKU:ES6312
ATBF1 rabbit pAb
ATBF1 rabbit pAb
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$250.00 USD
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Applications: IHC;IF;ELISA
Reactivity: Human;Mouse
Source: Rabbit
Dilution: Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human ZFHX3. AA range:761-810
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Human_gene_id: 463
Human_swiss_prot_no: Q15911
Subcellular_location: Nucleus . Cytoplasm . Translocates from the cytoplasm to the nucleus following TGF-beta stimulation. Expressed in nuclear body (NB)-like dots in the nucleus some of which overlap or closely associate with PML body. .
Other_name: ZFHX3; ATBF1; Zinc finger homeobox protein 3; AT motif-binding factor; AT-binding transcription factor 1; Alpha-fetoprotein enhancer-binding protein; Zinc finger homeodomain protein 3; ZFH-3
Background: This gene encodes a transcription factor with multiple homeodomains and zinc finger motifs, and regulates myogenic and neuronal differentiation. The encoded protein suppresses expression of the alpha-fetoprotein gene by binding to an AT-rich enhancer motif. The protein has also been shown to negatively regulate c-Myb, and transactivate the cell cycle inhibitor cyclin-dependent kinase inhibitor 1A (also known as p21CIP1). This gene is reported to function as a tumor suppressor in several cancers, and sequence variants of this gene are also associated with atrial fibrillation. Multiple transcript variants expressed from alternate promoters and encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009],
Reactivity: Human;Mouse
Source: Rabbit
Dilution: Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human ZFHX3. AA range:761-810
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Human_gene_id: 463
Human_swiss_prot_no: Q15911
Subcellular_location: Nucleus . Cytoplasm . Translocates from the cytoplasm to the nucleus following TGF-beta stimulation. Expressed in nuclear body (NB)-like dots in the nucleus some of which overlap or closely associate with PML body. .
Other_name: ZFHX3; ATBF1; Zinc finger homeobox protein 3; AT motif-binding factor; AT-binding transcription factor 1; Alpha-fetoprotein enhancer-binding protein; Zinc finger homeodomain protein 3; ZFH-3
Background: This gene encodes a transcription factor with multiple homeodomains and zinc finger motifs, and regulates myogenic and neuronal differentiation. The encoded protein suppresses expression of the alpha-fetoprotein gene by binding to an AT-rich enhancer motif. The protein has also been shown to negatively regulate c-Myb, and transactivate the cell cycle inhibitor cyclin-dependent kinase inhibitor 1A (also known as p21CIP1). This gene is reported to function as a tumor suppressor in several cancers, and sequence variants of this gene are also associated with atrial fibrillation. Multiple transcript variants expressed from alternate promoters and encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009],
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