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ELK Biotechnology

SKU:ES6033

Cytokeratin 14/16 rabbit pAb

Cytokeratin 14/16 rabbit pAb

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Applications: WB;IHC;IF;ELISA
Reactivity: Human;Mouse;Rat
Source: Rabbit
Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human Keratin 14. AA range:1-50
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed_band(KD): 52kD
Human_gene_id: 3861/3868/3872
Human_swiss_prot_no: P02533/P08779
Subcellular_location: Cytoplasm. Nucleus. Expressed in both as a filamentous pattern.
Other_name: KRT14; Keratin; type I cytoskeletal 14; Cytokeratin-14; CK-14; Keratin-14; K14; KRT16; KRT16A; Keratin, type I cytoskeletal 16; Cytokeratin-16; CK-16; Keratin-16; K16
Background: This gene encodes a member of the keratin family, the most diverse group of intermediate filaments. This gene product, a type I keratin, is usually found as a heterotetramer with two keratin 5 molecules, a type II keratin. Together they form the cytoskeleton of epithelial cells. Mutations in the genes for these keratins are associated with epidermolysis bullosa simplex. At least one pseudogene has been identified at 17p12-p11. [provided by RefSeq, Jul 2008],
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