E-Ras rabbit pAb

Applications: WB;IF;ELISA
Reactivity: Human;Rat;Mouse;
Source: Rabbit
Dilution: Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human ERAS. AA range:184-233
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed_band(KD): 25kD
Human_gene_id: 3266
Human_swiss_prot_no: Q7Z444
Subcellular_location: Cell membrane ; Lipid-anchor ; Cytoplasmic side .
Other_name: ERAS; HRAS2; HRASP; GTPase ERas; E-Ras; Embryonic stem cell-expressed Ras
Background: This gene encodes a constitutively active member of the small GTPase Ras protein family. The encoded protein activates the phosphatidylinositol 3-kinase signal transduction pathway in undifferentiated stem cells, but is not expressed in differentiated cells. This gene may be involved in cancer and chemotherapy resistance. [provided by RefSeq, Dec 2012],