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ELK Biotechnology

SKU:ES5378

Rab 38 rabbit pAb

Rab 38 rabbit pAb

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Size
Applications: WB;IHC
Reactivity: Human;Mouse;Rat
Source: Rabbit
Dilution: WB 1:500-2000;IHC-p 1:50-300
Immunogen: The antiserum was produced against synthesized peptide derived from human RAB38. AA range:80-129
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed_band(KD): 26kD
Human_gene_id: 23682
Human_swiss_prot_no: P57729
Subcellular_location: Cell membrane ; Lipid-anchor ; Cytoplasmic side . Melanosome . Cytoplasmic vesicle, phagosome . Cytoplasmic vesicle, phagosome membrane ; Lipid-anchor ; Cytoplasmic side . Melanosome membrane . Recruited to phagosomes containing S.aureus or M.tuberculosis (PubMed:21255211). The BLOC-3 complex, a heterodimer of HPS1 and HPS4 promotes its membrane localization (PubMed:23084991). .
Other_name: RAB38; Ras-related protein Rab-38; Melanoma antigen NY-MEL-1
Background: function:May be involved in melanosomal transport and docking. Involved in the proper sorting of TYRP1.,PTM:Although at least one in vitro system can process and methylate the prenylated C-terminal, in an in vitro system that normally express Rab-38 and in vivo the prenylated C-terminal is not proteolytically processed and not methylated.,similarity:Belongs to the small GTPase superfamily. Rab family.,tissue specificity:Expressed in melanocytes.,
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