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ELK Biotechnology

SKU:ES4959

DGK-η rabbit pAb

DGK-η rabbit pAb

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Size
Applications: IHC;IF;ELISA
Reactivity: Human;Mouse
Source: Rabbit
Dilution: Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human DGKH. AA range:771-820
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Human_gene_id: 160851
Human_swiss_prot_no: Q86XP1
Subcellular_location: Cytoplasm . Cell membrane . Translocated from the cytoplasm to endosomes in response to stress stimuli (PubMed:12810723). Isoform 2 is rapidly relocated back to the cytoplasm upon removal of stress stimuli, whereas isoform 1 exhibits sustained endosomal association (PubMed:12810723). Translocates from the cytoplasm to the cell membrane in the presence of active GTP-bound form of HRAS (PubMed:19710016).
Other_name: DGKH; Diacylglycerol kinase eta; DAG kinase eta; Diglyceride kinase eta; DGK-eta
Background: diacylglycerol kinase eta(DGKH) Homo sapiens This gene encodes a member of the diacylglycerol kinase (DGK) enzyme family. Members of this family are involved in regulating intracellular concentrations of diacylglycerol and phosphatidic acid. Variation in this gene has been associated with bipolar disorder. Alternatively spliced transcript variants have been identified. [provided by RefSeq, Jul 2014],
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