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ELK Biotechnology

SKU:ES4756

COL13A1 rabbit pAb

COL13A1 rabbit pAb

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Applications: IF;ELISA
Reactivity: Human;Mouse
Source: Rabbit
Dilution: Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human Collagen XIII alpha1. AA range:641-690
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed_band(KD): 70kD
Human_gene_id: 1305
Human_swiss_prot_no: Q5TAT6
Subcellular_location: Cell membrane ; Single-pass type II membrane protein . Cell junction, synapse, postsynaptic cell membrane .
Other_name: COL13A1; Collagen alpha-1(XIII) chain; COLXIIIA1
Background: This gene encodes the alpha chain of one of the nonfibrillar collagens. The function of this gene product is not known, however, it has been detected at low levels in all connective tissue-producing cells so it may serve a general function in connective tissues. Unlike most of the collagens, which are secreted into the extracellular matrix, collagen XIII contains a transmembrane domain and the protein has been localized to the plasma membrane. The transcripts for this gene undergo complex and extensive splicing involving at least eight exons. Like other collagens, collagen XIII is a trimer; it is not known whether this trimer is composed of one or more than one alpha chain isomer. A number of alternatively spliced transcript variants have been described, but the full length nature of some of them has not been determined. [provided by RefSeq, Jul 2008],
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