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ELK Biotechnology

SKU:ES4632

VPS26B rabbit pAb

VPS26B rabbit pAb

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Size
Applications: WB;ELISA
Reactivity: Human;Mouse
Source: Rabbit
Dilution: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human VPS26B. AA range:231-280
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed_band(KD): 45kD
Human_gene_id: 112936
Human_swiss_prot_no: Q4G0F5
Subcellular_location: Cytoplasm . Membrane; Peripheral membrane protein . Early endosome . Late endosome . Localizes to early and late endosomal structures (By similarity). .
Other_name: VPS26B; Vacuolar protein sorting-associated protein 26B; Vesicle protein sorting 26B
Background: function:Probable component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the VPS26 family.,subcellular location:Does not localize to endosomes.,subunit:Probable component of the retromer complex composed of VPS26 (VPS26A or VPS26B), VPS29, VPS35, SNX1 and SNX2. Interacts directly with VPS35.,
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