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ELK Biotechnology

SKU:ES4615

Frizzled-10 rabbit pAb

Frizzled-10 rabbit pAb

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Applications: WB;IHC;IF;ELISA
Reactivity: Human;Mouse;Monkey
Source: Rabbit
Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human FZD10. AA range:135-184
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed_band(KD): 60kD
Human_gene_id: 11211
Human_swiss_prot_no: Q9ULW2
Subcellular_location: Cell membrane ; Multi-pass membrane protein .
Other_name: FZD10; Frizzled-10; Fz-10; hFz10; FzE7; CD antigen CD350
Background: This gene is a member of the frizzled gene family. Members of this family encode 7-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. Using array analysis, expression of this intronless gene is significantly up-regulated in two cases of primary colon cancer. [provided by RefSeq, Jul 2008],
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