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ELK Biotechnology
SKU:ES4050
NUMB rabbit pAb
NUMB rabbit pAb
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$250.00 USD
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$250.00 USD
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Applications: WB; IF;ELISA
Reactivity: Human;Mouse;Rat
Source: Rabbit
Dilution: WB 1:500-2000; IF/ICC 1:100-500;ELISA 1:5000-20000
Immunogen: Synthesized peptide derived from the Internal region of human NUMB.
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed_band(KD): 70kD
Human_gene_id: 8650
Human_swiss_prot_no: P49757
Subcellular_location: Cell membrane ; Peripheral membrane protein ; Cytoplasmic side . Endosome membrane ; Peripheral membrane protein ; Cytoplasmic side . Localizes to perinuclear endosomes in an AAK1-dependent manner. .
Other_name: NUMB; Protein numb homolog; h-Numb; Protein S171
Background: The protein encoded by this gene plays a role in the determination of cell fates during development. The encoded protein, whose degradation is induced in a proteasome-dependent manner by MDM2, is a membrane-bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016],
Reactivity: Human;Mouse;Rat
Source: Rabbit
Dilution: WB 1:500-2000; IF/ICC 1:100-500;ELISA 1:5000-20000
Immunogen: Synthesized peptide derived from the Internal region of human NUMB.
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed_band(KD): 70kD
Human_gene_id: 8650
Human_swiss_prot_no: P49757
Subcellular_location: Cell membrane ; Peripheral membrane protein ; Cytoplasmic side . Endosome membrane ; Peripheral membrane protein ; Cytoplasmic side . Localizes to perinuclear endosomes in an AAK1-dependent manner. .
Other_name: NUMB; Protein numb homolog; h-Numb; Protein S171
Background: The protein encoded by this gene plays a role in the determination of cell fates during development. The encoded protein, whose degradation is induced in a proteasome-dependent manner by MDM2, is a membrane-bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016],