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ELK Biotechnology

SKU:ES3420

SENP5 rabbit pAb

SENP5 rabbit pAb

Regular price $250.00 USD
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Size
Applications: WB;IHC;IF;ELISA
Reactivity: Human;Mouse;Monkey
Source: Rabbit
Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human SENP5. AA range:651-700
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed_band(KD): 86kD
Human_gene_id: 205564
Human_swiss_prot_no: Q96HI0
Subcellular_location: Nucleus, nucleolus .
Other_name: SENP5; FKSG45; Sentrin-specific protease 5; Sentrin/SUMO-specific protease SENP5
Background: The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins (see SUMO1; MIM 601912) is required for numerous biologic processes. SUMO-specific proteases, such as SENP5, are responsible for the initial processing of SUMO precursors to generate a C-terminal diglycine motif required for the conjugation reaction. They also have isopeptidase activity for the removal of SUMO from high molecular mass SUMO conjugates (Di Bacco et al., 2006 [PubMed 16738315]).[supplied by OMIM, Jun 2009],
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