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ELK Biotechnology

SKU:ES3279

PTH rabbit pAb

PTH rabbit pAb

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Size
Applications: WB;IHC
Reactivity: Human;Rat;Mouse;
Source: Rabbit
Dilution: WB 1:500-2000;IHC-p 1:50-300
Immunogen: The antiserum was produced against synthesized peptide derived from human Parathyroid Hormone. AA range:51-100
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed_band(KD): 16kD
Human_gene_id: 5741
Human_swiss_prot_no: P01270
Subcellular_location: Secreted.
Other_name: PTH; Parathyroid hormone; PTH; Parathormone; Parathyrin
Background: This gene encodes a member of the parathyroid family of proteins. The encoded preproprotein is proteolytically processed to generate a protein that binds to the parathyroid hormone/parathyroid hormone-related peptide receptor and regulates blood calcium and phosphate levels. Excess production of the encoded protein, known as hyperparathyroidism, can result in hypercalcemia and kidney stones. On the other hand, defective processing of the encoded protein may lead to hypoparathyroidism, which can result in hypocalcemia and numbness. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015],
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