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ELK Biotechnology

SKU:ES3263

PRPF18 rabbit pAb

PRPF18 rabbit pAb

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Applications: WB;ELISA;IHC
Reactivity: Human;Mouse;Rat
Source: Rabbit
Dilution: WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
Immunogen: The antiserum was produced against synthesized peptide derived from human PRPF18. AA range:182-231
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed_band(KD): 40kD
Human_gene_id: 8559
Human_swiss_prot_no: Q99633
Subcellular_location: Nucleus speckle . Colocalizes with spliceosomal snRNPs. .
Other_name: PRPF18; HPRP18; Pre-mRNA-splicing factor 18; PRP18 homolog; hPRP18
Background: Pre-mRNA splicing occurs in 2 sequential transesterification steps. The protein encoded by this gene is found to be essential for the catalytic step II in pre-mRNA splicing process. It is found in the spliceosome, and contains seven WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to the yeast splicing factor Prp18. [provided by RefSeq, Jul 2008],
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