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ELK Biotechnology
SKU:ES3245
POT1 rabbit pAb
POT1 rabbit pAb
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$250.00 USD
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Applications: WB;IHC
Reactivity: Human;Monkey
Source: Rabbit
Dilution: WB 1:500-2000;IHC-p 1:50-300
Immunogen: The antiserum was produced against synthesized peptide derived from human POT1. AA range:247-296
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed_band(KD): 70kD
Human_gene_id: 25913
Human_swiss_prot_no: Q9NUX5
Subcellular_location: Nucleus . Chromosome, telomere . Colocalizes with telomeric DNA.
Other_name: POT1; Protection of telomeres protein 1; hPot1; POT1-like telomere end-binding protein
Background: protection of telomeres 1(POT1) Homo sapiens This gene is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of this gene is associated with stomach carcinogenesis and its progression. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008],
Reactivity: Human;Monkey
Source: Rabbit
Dilution: WB 1:500-2000;IHC-p 1:50-300
Immunogen: The antiserum was produced against synthesized peptide derived from human POT1. AA range:247-296
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed_band(KD): 70kD
Human_gene_id: 25913
Human_swiss_prot_no: Q9NUX5
Subcellular_location: Nucleus . Chromosome, telomere . Colocalizes with telomeric DNA.
Other_name: POT1; Protection of telomeres protein 1; hPot1; POT1-like telomere end-binding protein
Background: protection of telomeres 1(POT1) Homo sapiens This gene is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of this gene is associated with stomach carcinogenesis and its progression. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008],
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