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ELK Biotechnology
SKU:ES3232
Plakophilin 2 rabbit pAb
Plakophilin 2 rabbit pAb
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$250.00 USD
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Applications: WB;ELISA;IHC
Reactivity: Human;Rat
Source: Rabbit
Dilution: WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
Immunogen: The antiserum was produced against synthesized peptide derived from human PKP2. AA range:632-681
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed_band(KD): 97kD
Human_gene_id: 5318
Human_swiss_prot_no: Q99959
Subcellular_location: Nucleus . Cell junction, desmosome . Nuclear and associated with desmosomes.
Other_name: PKP2; Plakophilin-2
Background: This gene encodes a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. This gene product may regulate the signaling activity of beta-catenin. Two alternately spliced transcripts encoding two protein isoforms have been identified. A processed pseudogene with high similarity to this locus has been mapped to chromosome 12p13. [provided by RefSeq, Jul 2008],
Reactivity: Human;Rat
Source: Rabbit
Dilution: WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
Immunogen: The antiserum was produced against synthesized peptide derived from human PKP2. AA range:632-681
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed_band(KD): 97kD
Human_gene_id: 5318
Human_swiss_prot_no: Q99959
Subcellular_location: Nucleus . Cell junction, desmosome . Nuclear and associated with desmosomes.
Other_name: PKP2; Plakophilin-2
Background: This gene encodes a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. This gene product may regulate the signaling activity of beta-catenin. Two alternately spliced transcripts encoding two protein isoforms have been identified. A processed pseudogene with high similarity to this locus has been mapped to chromosome 12p13. [provided by RefSeq, Jul 2008],
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