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ELK Biotechnology
SKU:ES2895
Nanog P8 rabbit pAb
Nanog P8 rabbit pAb
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$250.00 USD
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Applications: WB;IF;ELISA;IHC
Reactivity: Human;Rat;Mouse;
Source: Rabbit
Dilution: WB 1:500-2000; IF/ICC 1:50-200;ELISA 1:2000-20000;IHC-p 1:50-200
Immunogen: The antiserum was produced against synthesized peptide derived from human NANOGP8. AA range:51-100
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed_band(KD): 35kD
Human_gene_id: 388112
Human_swiss_prot_no: Q6NSW7
Subcellular_location: Nucleus .
Other_name: NANOGP8; Putative homeobox protein NANOGP8
Background: This locus is a processed pseudogene of the transcription factor NANOG. NANOG plays a central role in regulating self-renewal in pluripotent stem cells and tumor cells. This pseudogene contains an intact open reading frame that could potentially encode a protein similar to NANOG. Although there is no evidence of transcription from this pseudogene, RT-PCR studies suggest that NANOGP8 may be expressed in some cancer cell lines. In vitro studies using a recombinant NANOGP8 protein have shown that the protein localizes to the nucleus and can promote cell proliferation, similar to NANOG. [provided by RefSeq, Sep 2009],
Reactivity: Human;Rat;Mouse;
Source: Rabbit
Dilution: WB 1:500-2000; IF/ICC 1:50-200;ELISA 1:2000-20000;IHC-p 1:50-200
Immunogen: The antiserum was produced against synthesized peptide derived from human NANOGP8. AA range:51-100
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed_band(KD): 35kD
Human_gene_id: 388112
Human_swiss_prot_no: Q6NSW7
Subcellular_location: Nucleus .
Other_name: NANOGP8; Putative homeobox protein NANOGP8
Background: This locus is a processed pseudogene of the transcription factor NANOG. NANOG plays a central role in regulating self-renewal in pluripotent stem cells and tumor cells. This pseudogene contains an intact open reading frame that could potentially encode a protein similar to NANOG. Although there is no evidence of transcription from this pseudogene, RT-PCR studies suggest that NANOGP8 may be expressed in some cancer cell lines. In vitro studies using a recombinant NANOGP8 protein have shown that the protein localizes to the nucleus and can promote cell proliferation, similar to NANOG. [provided by RefSeq, Sep 2009],
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