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ELK Biotechnology

SKU:ES2639

IQGAP1 rabbit pAb

IQGAP1 rabbit pAb

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Size
Applications: WB;IHC
Reactivity: Human;Mouse
Source: Rabbit
Dilution: WB 1:500-2000;IHC-p 1:50-300
Immunogen: The antiserum was produced against synthesized peptide derived from human IQGAP1. AA range:247-296
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed_band(KD): 190kD
Human_gene_id: 8826
Human_swiss_prot_no: P46940
Subcellular_location: Cell membrane . Nucleus . Cytoplasm . Subcellular distribution is regulated by the cell cycle, nuclear levels increase at G1/S phase (PubMed:20883816). .
Other_name: IQGAP1; KIAA0051; Ras GTPase-activating-like protein IQGAP1; p195
Background: IQ motif containing GTPase activating protein 1(IQGAP1) Homo sapiens This gene encodes a member of the IQGAP family. The protein contains four IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. It interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. Expression of the protein is upregulated by gene amplification in two gastric cancer cell lines. [provided by RefSeq, Jul 2008],
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