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ELK Biotechnology

SKU:ES2556

HoxA11/D11 rabbit pAb

HoxA11/D11 rabbit pAb

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Applications: WB;IHC;IF;ELISA
Reactivity: Human;Mouse
Source: Rabbit
Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human HOXA11/D11. AA range:216-265
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed_band(KD): 28kD
Human_gene_id: 3207/3237
Human_swiss_prot_no: P31270/P31277
Subcellular_location: Nucleus.
Other_name: HOXA11; HOX1I; Homeobox protein Hox-A11; Homeobox protein Hox-1I; HOXD11; HOX4F; Homeobox protein Hox-D11; Homeobox protein Hox-4F
Background: In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. This gene is involved in the regulation of uterine development and is required for female fertility. Mutations in this gene can cause radio-ulnar synostosis with amegakaryocytic thrombocytopenia. [provided by RefSeq, Jul 2008],
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