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ELK Biotechnology
SKU:ES2545
hnRNP A2/B1 rabbit pAb
hnRNP A2/B1 rabbit pAb
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Applications: WB;IHC;IF;ELISA
Reactivity: Human;Mouse
Source: Rabbit
Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human hnRNP A2/B1. AA range:1-50
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed_band(KD): 36+38kD
Human_gene_id: 3181
Human_swiss_prot_no: P22626
Subcellular_location: Nucleus . Nucleus, nucleoplasm . Cytoplasm . Cytoplasmic granule . Secreted, extracellular exosome . Localized in cytoplasmic mRNP granules containing untranslated mRNAs (PubMed:17289661). Component of ribonucleosomes (PubMed:17289661). Not found in the nucleolus (PubMed:17289661). Found in exosomes following sumoylation (PubMed:24356509). .; [Isoform A2]: Nucleus . Cytoplasm . Predominantly nucleoplasmic, however is also found in the cytoplasm of cells in some tissues (PubMed:17289661). .
Other_name: HNRNPA2B1; HNRPA2B1; Heterogeneous nuclear ribonucleoproteins A2/B1; hnRNP A2/B1
Background: This gene belongs to the A/B subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. This gene has been described to generate two alternatively spliced transcript variants which encode different isoforms. [provided by RefSeq, Jul 2008],
Reactivity: Human;Mouse
Source: Rabbit
Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human hnRNP A2/B1. AA range:1-50
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed_band(KD): 36+38kD
Human_gene_id: 3181
Human_swiss_prot_no: P22626
Subcellular_location: Nucleus . Nucleus, nucleoplasm . Cytoplasm . Cytoplasmic granule . Secreted, extracellular exosome . Localized in cytoplasmic mRNP granules containing untranslated mRNAs (PubMed:17289661). Component of ribonucleosomes (PubMed:17289661). Not found in the nucleolus (PubMed:17289661). Found in exosomes following sumoylation (PubMed:24356509). .; [Isoform A2]: Nucleus . Cytoplasm . Predominantly nucleoplasmic, however is also found in the cytoplasm of cells in some tissues (PubMed:17289661). .
Other_name: HNRNPA2B1; HNRPA2B1; Heterogeneous nuclear ribonucleoproteins A2/B1; hnRNP A2/B1
Background: This gene belongs to the A/B subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. This gene has been described to generate two alternatively spliced transcript variants which encode different isoforms. [provided by RefSeq, Jul 2008],
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