1
/
of
1
ELK Biotechnology
SKU:ES20862
ATG13 Rabbit pAb
ATG13 Rabbit pAb
Regular price
$250.00 USD
Regular price
Sale price
$250.00 USD
Unit price
/
per
Shipping calculated at checkout.
Couldn't load pickup availability
Applications: IHC;WB
Reactivity: Human; Mouse;Rat
Source: Rabbit
Dilution: IHC-p1:50-200 ,WB 1:1000-2000
Immunogen: Synthesized peptide derived from human ATG13 AA range: 182-232
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed_band(KD): 72kD
Human_gene_id: 9776
Human_swiss_prot_no: O75143
Subcellular_location: Cytoplasm, cytosol . Preautophagosomal structure . Under starvation conditions, is localized to puncate structures primarily representing the isolation membrane; the isolation membrane sequesters a portion of the cytoplasm resulting in autophagosome formation. .
Other_name: Autophagy-related protein 13
Background: Atg13 was identified as a constitutively expressed protein that was genetically linked to Atg1/Apg1, a protein kinase required for autophagy. Overexpression of Atg1 suppresses the defects in autophagy observed in Atg13 mutants. Autophagy requires a direct association between Atg1 and Atg13, and is inhibited by TOR-dependent phosphorylation of Atg13 under high-nutrient conditions.
Reactivity: Human; Mouse;Rat
Source: Rabbit
Dilution: IHC-p1:50-200 ,WB 1:1000-2000
Immunogen: Synthesized peptide derived from human ATG13 AA range: 182-232
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed_band(KD): 72kD
Human_gene_id: 9776
Human_swiss_prot_no: O75143
Subcellular_location: Cytoplasm, cytosol . Preautophagosomal structure . Under starvation conditions, is localized to puncate structures primarily representing the isolation membrane; the isolation membrane sequesters a portion of the cytoplasm resulting in autophagosome formation. .
Other_name: Autophagy-related protein 13
Background: Atg13 was identified as a constitutively expressed protein that was genetically linked to Atg1/Apg1, a protein kinase required for autophagy. Overexpression of Atg1 suppresses the defects in autophagy observed in Atg13 mutants. Autophagy requires a direct association between Atg1 and Atg13, and is inhibited by TOR-dependent phosphorylation of Atg13 under high-nutrient conditions.
Share
