ATG14L Rabbit rabbit pAb

Applications: IHC;IF
Reactivity: Human;Mouse;Rat
Source: Rabbit
Dilution: IHC-p 1:50-300
Immunogen: Recombinant Protein of ATG14L
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed_band(KD): 55kD
Human_gene_id: 22863
Human_swiss_prot_no: Q6ZNE5
Subcellular_location: Cytoplasm . Endoplasmic reticulum membrane ; Peripheral membrane protein . Preautophagosomal structure membrane ; Peripheral membrane protein . Cytoplasmic vesicle, autophagosome membrane ; Peripheral membrane protein . Cytosolic under nutrient-rich conditions (PubMed:19050071). Following autophagy stimuli, such as starvation or rapamycin induction, predominantly detected in cytoplasmic foci, identified as isolation membranes and autophagosomes (PubMed:19050071). Accumulates on highly curved PtdIns(3)P enriched autophagic membrane via its BATS domain to sense and maintain membrane curvature (By similarity). Localizes also to discrete punctae along the ciliary axoneme and to the base of the ciliary axoneme (By similarity). .
Other_name: Beclin 1-associated autophagy-related key regulator (Barkor;Autophagy-related protein 14-like protein;Atg14L)
Background: miscellaneous:The sequence shown here is derived from an EMBL/GenBank/DDBJ third party annotation (TPA) entry.,